Leftover Pizza Chicken Sandwich

Featured in: Cozy Everyday Dinners

This indulgent sandwich transforms leftover pizza slices into a crispy bread alternative, stuffed with tender shredded chicken, fresh peppery arugula, and melted mozzarella cheese. The combined textures create a comforting bite, quickly grilled with olive oil or butter for golden crust perfection. Seasoned lightly with black pepper and optional salt, it offers versatility with variations like barbecue or pesto chicken and alternative greens. A flavorful, easy dish to enjoy creative comfort food with minimal prep time.

Updated on Fri, 19 Dec 2025 13:52:00 GMT
Golden, cheesy Leftover Pizza Chicken Sandwich, overflowing with shredded chicken and peppery arugula, ready to eat. Save to Pinterest
Golden, cheesy Leftover Pizza Chicken Sandwich, overflowing with shredded chicken and peppery arugula, ready to eat. | orchardbowl.com

I was staring at two cold slices of pepperoni pizza on a Tuesday night, too tired to cook but too hungry to ignore my stomach. My roommate walked in, saw the leftover rotisserie chicken, and said, "What if you just made a sandwich out of it?" I laughed at first, then grabbed the skillet. Twenty minutes later, we were fighting over who got the crispier half.

The first time I served this to my sister, she picked it up, tilted her head, and said, "This is either genius or chaos." After one bite, she went quiet, nodded slowly, and asked if I had more pizza in the fridge. I didn't, but I've kept extra slices around ever since. It became our official late night snack whenever we're together, no questions asked.

Ingredients

  • Cold leftover pizza slices: The crust gets crispier when it's been refrigerated overnight, and any topping works as long as the slices are similar in size so the sandwich holds together.
  • Cooked shredded chicken: Rotisserie is my favorite because it's already seasoned and juicy, but any leftover chicken works, just warm it slightly first if it's straight from the fridge.
  • Fresh arugula: The peppery bite cuts through all the richness and adds a fresh crunch that keeps the sandwich from feeling too heavy.
  • Shredded mozzarella or Italian cheese blend: Mozzarella melts beautifully and stretches, but a blend with provolone or fontina adds even more flavor.
  • Mayonnaise: I skip it sometimes, but when I use it, it adds moisture and helps the filling stick to the pizza without making it soggy.
  • Olive oil or softened butter: Butter gives a richer, golden crust, olive oil keeps it a little lighter, both work perfectly depending on your mood.
  • Freshly ground black pepper and salt: The pizza is usually salty enough, so I go easy on the salt and let the pepper do most of the work.

Instructions

Prep the Pizza Slices:
Lay two slices crust side down on your cutting board. If you're using mayo, spread a whisper thin layer on the inside, it adds richness without making things slippery.
Layer the Chicken:
Divide the shredded chicken evenly between the two slices, then season with black pepper and a tiny pinch of salt if your pizza isn't already salty. Press it down gently so it doesn't slide out later.
Add Greens and Cheese:
Pile on the arugula, don't be shy, it wilts a little when the sandwich heats up. Then scatter the shredded cheese generously over the top so every bite gets gooey.
Close the Sandwiches:
Top with the remaining pizza slices, crust side up, pressing down lightly to seal everything together. It should feel sturdy but not squished.
Heat the Skillet:
Warm your olive oil or butter in a large nonstick skillet over medium heat until it shimmers but doesn't smoke. Medium heat is key, too high and the crust burns before the cheese melts.
Grill the Sandwiches:
Place both sandwiches in the skillet and press gently with a spatula. Cook for three to four minutes per side until the crust turns golden and crisp and the cheese inside is fully melted and stretchy.
Rest and Serve:
Pull them off the heat and let them sit for one minute so the cheese sets just enough to not spill everywhere. Slice in half and serve hot.
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| orchardbowl.com

One night, my brother came over after a long shift and I handed him one of these without explaining what it was. He took a huge bite, paused mid chew, and started laughing. He said it tasted like every good decision he'd ever made in one sandwich. Now, whenever he visits, he checks the fridge for leftover pizza before he even says hello.

Flavor Variations You'll Actually Use

I've made this with buffalo chicken and a drizzle of ranch inside, and it was dangerously good. Barbecue chicken with red onion and cilantro works beautifully if your pizza base is mild. Pesto chicken with sun dried tomatoes and mozzarella turns it into something fancy enough for lunch guests. If you want it spicy, toss the chicken in hot sauce or sprinkle red pepper flakes right before you close the sandwich.

What to Serve Alongside

A small bowl of warm marinara for dipping is my go to, it feels like you're eating pizza and a sandwich at the same time in the best way. I've also served it with a simple side salad dressed in lemon and olive oil to balance the richness. If you're feeling indulgent, crispy potato wedges or sweet potato fries make it a full comfort meal. Sometimes I just eat it alone with a cold drink and call it perfect.

Storage and Reheating Tips

Honestly, this is best eaten fresh because the crust loses its crispness once it sits. If you have leftovers, wrap them tightly and refrigerate for up to one day. Reheat in a skillet over medium low heat, not the microwave, or it'll turn soggy. You can also pop it in a preheated oven at 375 degrees for about eight minutes to crisp it back up.

  • Let it cool completely before wrapping to avoid steam making the crust soft.
  • Don't stack multiple sandwiches on top of each other in the fridge, they'll stick together.
  • If you're meal prepping, assemble but don't cook them, then grill fresh when you're ready to eat.
Grilled Leftover Pizza Chicken Sandwich cut open, revealing melted cheese and tender chicken layered in the crusty bread. Save to Pinterest
Grilled Leftover Pizza Chicken Sandwich cut open, revealing melted cheese and tender chicken layered in the crusty bread. | orchardbowl.com

This recipe taught me that leftovers don't have to feel like leftovers, they can feel like a brand new idea that's even better than the original. I hope yours turns out crispy, cheesy, and exactly as satisfying as mine always does.

Recipe Questions & Answers

Can I use any type of leftover pizza for this sandwich?

Yes, any pizza type works best when slices are similar in size and thickness to ensure even grilling and sturdy sandwich layers.

What cheese works best for melting inside the sandwich?

Shredded mozzarella or an Italian cheese blend melts well and complements the flavors without overpowering the chicken or arugula.

Is it necessary to use mayonnaise in the sandwich?

Mayonnaise is optional; it adds moisture and subtle creaminess but can be omitted for a lighter option or replaced with other spreads.

How can I make the sandwich vegetarian?

Simply replace shredded chicken with roasted vegetables like mushrooms or peppers to maintain a hearty filling.

What are some good variations for the chicken filling?

Try barbecue, buffalo, or pesto-seasoned chicken to add different flavor profiles that complement the pizza crust base.

How should the sandwich be cooked for best results?

Grill the sandwich in a nonstick skillet with olive oil or butter over medium heat, pressing gently to achieve a golden, crisp crust and melted cheese.

Leftover Pizza Chicken Sandwich

Juicy shredded chicken and melted cheese layered between crispy leftover pizza slices in a satisfying twist.

Prep Time
10 minutes
Time to Cook
10 minutes
Overall Time
20 minutes
Created by Sophie Alden

Recipe Type Cozy Everyday Dinners

Skill Level Easy

Cuisine Origin American/Italian Fusion

Makes 2 Number of Servings

Dietary Details None specified

What You'll Need

Sandwich components

01 4 cold leftover pizza slices (any variety, similar size and thickness)
02 1 cup cooked shredded chicken (rotisserie or leftover)
03 1 cup fresh arugula
04 1 cup shredded mozzarella or Italian cheese blend
05 2 tbsp mayonnaise (optional)
06 1 tbsp olive oil or softened butter (for grilling)

Seasonings

01 1/4 tsp freshly ground black pepper
02 Pinch of salt (optional, adjust based on pizza saltiness)

How To Make It

Step 01

Prepare pizza base: Arrange two pizza slices crust-side down on a clean cutting board. Optionally, spread a thin layer of mayonnaise on the inner side of each slice for added moisture and flavor.

Step 02

Add chicken and seasonings: Evenly distribute shredded chicken over each pizza slice. Season with freshly ground black pepper and a pinch of salt if necessary.

Step 03

Layer arugula and cheese: Place a generous handful of fresh arugula atop the chicken, then sprinkle evenly with shredded mozzarella or Italian cheese blend.

Step 04

Assemble sandwiches: Cover each with the remaining pizza slices, crust-side up, creating two sandwiches.

Step 05

Heat skillet: Warm olive oil or softened butter in a large nonstick skillet over medium heat until shimmering.

Step 06

Grill sandwiches: Place sandwiches in skillet carefully. Press gently with a spatula and cook for 3 to 4 minutes on each side until cheese has melted and the pizza crust turns golden and crisp.

Step 07

Rest and serve: Transfer sandwiches from skillet and allow to rest for 1 minute. Slice in half and serve immediately.

Equipment Needed

  • Large nonstick skillet or grill pan
  • Spatula
  • Knife and cutting board

Allergy Warnings

Review all components for possible allergens and seek medical guidance if needed.
  • Contains wheat (pizza crust), dairy (cheese and possibly pizza toppings), and potentially eggs (mayonnaise and certain pizzas). Verify allergen information if using store-bought or restaurant pizza.

Nutrition Info (for each serving)

Details here are for your reference and aren't a substitute for professional advice.
  • Total Calories: 520
  • Total Fat: 24 grams
  • Carbohydrates: 44 grams
  • Proteins: 31 grams